Professor Sir Peter Ratcliffe FRS
Photo: © Adobe Stock
Dr Madeline Lancaster
Photo: © Dr Madeline Lancaster
Organisers: Professor Ashok Venkitaraman, Dr James Fraser and Dr Nick Pugh
Display at the Whipple Library showcases 200 Years of Scientific Publishing at the Cambridge Philosophical Society
Photo: © Jack Dixon
Photo: © Jim Woodhouse
Founded in 1819 'for the purpose of promoting scientific inquiry', The Cambridge Philosophical Society is an exciting hub for the promotion of scientific research, discussion, and learning. Discover more…
The maintenance of oxygen homeostasis is a key physiological challenge, inadequate oxygen (hypoxia) being a major component of most human diseases. The lecture will trace insights into human oxygen homeostasis from the founding work of William Harvey on the circulation of the blood to the molecular elucidation of a system of oxygen sensing that functions to measure oxygen levels in cells and control adaptive responses to hypoxia. The lecture will outline how the oxygen sensitive signal is generated by a set of ‘oxygen splitting’ enzymes that modify a transcription factor (HIF) to signal for its degradation (and hence inactivation). It will attempt to illustrate and rationalise the unexpected in biological discovery and discuss the interface of discovery science with the development of medical therapeutics.
Please Note: This lecture will NOT be recorded and is an in-person lecture only.
The human brain sets us apart as a species, yet how it develops and functions differently to that of other mammals is still largely unclear. This also makes it difficult to understand how disorders of the brain arise, and therefore how to treat them. To understand such a complex organ, we have developed cerebral organoids, or brain organoids, 3D brain tissues made from stem cells that mimic the fetal brain. Such organoids are allowing us to tackle questions previously impossible with more traditional approaches. Indeed, our recent findings provide insight into various factors that influence the developing brain, and how the human brain becomes so uniquely large enabling our special cognitive abilities.
Professor Lindsay Greer becomes the new CPS President for 2024-2026.
In line with the core aim of 'keeping alive the spirit of inquiry’, the Society awards a number financial grants for future scientists, which include a three-year Research Studentships, the Henslow Fellowship, in the fields of Natural Science, Engineering, Mathematics, Computer Science and Clinical Sciences. Travel Grants are for Fellows of the Society and help support researchers to attend conferences and visit laboratories.
From Darwin’s paper on evolution to the development of stem cell research, publications from the Society continue to shape the scientific landscape.
Mathematical Proceedings is one of the few high-quality journals publishing original research papers that cover the whole range of pure and applied mathematics, theoretical physics and statistics.
Biological Reviews covers the entire range of the biological sciences, presenting several review articles per issue. Although scholarly and with extensive bibliographies, the articles are aimed at non-specialist biologists as well as researchers in the field.
The Spirit of Inquiry celebrates the 200th anniversary of the remarkable Cambridge Philosophical Society and brings to life the many remarkable episodes and illustrious figures associated with the Society, including Adam Sedgwick, Mary Somerville, Charles Darwin, and Lawrence Bragg.
Become a Fellow of the Society and enjoy the benefits that membership brings. Membership costs £20 per year.
Cambridge Philosophical Society17 Mill LaneCambridgeCB2 1RXUnited Kingdom
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